Reactive transhumanism is a popular portrayal of transhumanist themes in media. Typically the premise involves an individual or small group gaining access to experimental technology perhaps via experimentation, some kind of Deus Ex machina or conventional scientific invention, perhaps in the mad scientist vein, either biological or cybernetic. Most of the super hero genre is predicated upon this.
- BioShock - Shoot the bad guys with super powers aka sci-fantasy/low fantasy style genetic engineering. BioShock 1 and 2 uses plasmids, where as BioShock Infinite uses "Vigors" for the same effect.
- Deus Ex - This game series allows the protagonist to shoot or sneak their way through their adventure, siding with multiple potential factions or none. Its transhumanist vision favours cybernetics or nanotechnology rather than biological superpowers.
- Fallout - There some factions (especially with Caesar's Legion and Brotherhood of Steel) have their versions, views and stance of which technology is harmful or not as a response made about aftermath from The Great War.
- Fracture - Set in near far future in 2160s that Climate Change is successfully ocean's rising water up, Main location sets in near final days of Second American Civil War with two Nations favoring their own idea of transhumanism is way surviving post-Climate Change earth
- "The Atlantic"/United States radically supported Cybernetic/Cyber related transhumanism as their way to survive.
- 'The Pacificans'/Pacific States of America a breakaway state from US/ASA. Strongly supported biotechnological related transhumanism as way to survived and unlike its enemy, they just actually want getting freedom and their transhuman rights back from US government's anti-Bio-transhuman laws that have forced people who are opposed.
Film and TV
- Limitless - Portrays an individual following his own agenda subject to a powerful nootropic.
- Agents of Shield - Depicted the rise of 'Inhumans', enhanced individuals who have a complex relationship with government regulation.
- Star Trek - The franchise in general explores various ideas around transhumanist and posthumanist concepts that rather have mixed results.